Exosomes in Cancer Diagnosis and Radiation Therapy

Exosomes are a subgroup of extracellular vesicles that released by all types cells, including tumor and mediate intercellular communication via the transport various intracellular components, microRNAs, messenger RNAs, proteins. Radiation produces reactive oxygen species induces DNA double-strand break in cancer cells normal cells. Cancer have severe damage die irradiation, but can keep proliferation with their high repair ability. Irradiated generate signals cause biological changes neighboring or distant non-irradiated This review outlines role exosomes radiation therapy. In microenvironment, considered to regulate cell survival, migration, resistance therapy interacting vascular endothelial immune Nowadays, is typically combined immunotherapy. Regulation activity may overcome problem Furthermore, attenuate chemotherapy transporting certain microRNA. The current evidence suggests be useful diagnosis treatment future.